Antitumor anthracycline derivatives

Details Antitumor anthracycline derivatives Antitumor anthracycline derivatives

C - Chemistry, Metallurgy

07

H

260/208.2

C07H 15/24 (2006.01) C07H 15/252 (2006.01)

Patent

CA 1136618

RD-9239A New Antitumor Anthracycline Derivatives Abstract of the Disclosure New anthracycline derivatives of adriamycin and daunomycin prepared by the tetrahydropyranylation, tetra- hydrofuranylation or the etherification of the C-4' hydroxyl group of the initial glycoside derivatives of the formula Image wherein R3 is a hydrogen atom or an alkanoyloxy or phenylacetyloxy group, and if necessary, deacylation at the C-14 position when C-14 has been acylated, are found to be useful anti- microbial and antitumor agents.

344911

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