Antitumor antibiotic

C - Chemistry – Metallurgy – 12 – P

Patent

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195/96, 530/15.0

C12P 21/00 (2006.01) A61K 35/66 (2006.01) C12P 1/06 (2006.01)

Patent

CA 1215337

ABSTRACT A novel antitumor antibiotic designated herein as BBM-1644 is produced by fermentation of Actinomadura sp. strain H710-49 (ATCC 39144 ). BBM-1644 inhibits gram-positive and acid-fast bacteria, induces prophage in lysogenic bacteria and inhibits the growth of tumors such as P388 leukemia in mice.

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