Antitumor antibiotic bu-3285t

C - Chemistry – Metallurgy – 12 – P

Patent

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195/107, 167/180

C12P 17/06 (2006.01) A61K 31/365 (2006.01) C07D 309/32 (2006.01) C12N 1/20 (2006.01)

Patent

CA 2020878

The present invention relates to the antitumor antibiotic compound BU-3285T and its preparation. The compound is obtained by culturing a new strain of Chainia rosea and demonstrates both antitumor and antifungal activity. It also relates to the desulfated derivative of BU-3285T which is obtained by treatment of BU-3285T with sulfatase enzyme. BU-3285T desulfate possesses antitumor activity.

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