C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 11/02 (2006.01) C07K 7/06 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2135587
The present invention relates to novel antitumor depsipeptides produced by Micromonospora strain 39500, ATCC 55011, and having the structural formula Image wherein R1 is 2-methylpropanoyl, and R2 is 2- methylpropanoyl, propanoyl or acetyl; or R1 is 3- methylbutanoyl, and R2 is 2-methylpropanoyl or 3- methylbutanoyl; or R1 is propanoyl, and R2 is acetyl or propanoyl.
Berry Ronald L.
Dabrah Thomas T.
Gustavson Donald R.
Hesler Grace A.
Lam Kin S.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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