Antitumor antibiotics bbm-2040 produced by streptomyces

Details Antitumor antibiotics bbm-2040 produced by streptomyces Antitumor antibiotics bbm-2040 produced by streptomyces

C - Chemistry, Metallurgy

12

P

195/105, 260/239

C12P 17/18 (2006.01) C07D 487/04 (2006.01) C12N 1/20 (2006.01)

Patent

CA 1213542

ABSTRACT A novel antitumor antibiotic designated herein as BBM-2040 is produced by fermentation of Streptomyces sp. strain J576-99 (ATCC 39143 ). BBM-2040, which may be recovered from the fermentation broth in either a desmethanol (BBM-2040B) or methanol-adduct (BBM-2040A) form, inhibits gram-positive and acid-fast bacteria and inhibits the growth of tumors such as P388 leukemia in mice.

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