C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/025 (2006.01) A61K 39/12 (2006.01) C12N 15/86 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2296797
The invention concerns an antitumoral composition comprising as therapeutic agent one or several immunogenic polypeptides, of which at least one is modified so as to have a cell location different from its native location. The invention also concerns a composition based on a recombinant vector expressing said immunogenic polypeptide. It further concerns a recombinant vector comprising at least the sequences coding for an immunogenic polypeptide originating from a precocious and/or tardive region of a papillomavirus having a modified location and a viral particle comprising said vector. Finally it concerns the therapeutic use of said composition, said recombinant vector and said viral particle.
La présente invention concerne une composition antitumorale comprenant à titre d'agent thérapeutique un ou plusieurs polypeptides immunogènes, dont l'un au moins est modifié de manière à présenter une localisation cellulaire différente de sa localisation native. Elle concerne également une composition à base de vecteur recombinant exprimant ledit polypeptide immunogène. Elle a également pour objet un vecteur recombinant comprenant au moins les séquences codant pour un polypeptide immunogène originaire d'une région précoce et/ou tardive d'un papillomavirus modifié au niveau de sa localisation ainsi qu'une particule virale comprenant ledit vecteur. Enfin, elle concerne l'utilisation thérapeutique de la composition, du vecteur recombinant et de la particule virale selon l'invention.
Balloul Jean-Marc
Bizouarne Nadine
Kieny Marie-Paule
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Transgene S.a.
LandOfFree
Antitumoral composition based on immunogenic polypeptide... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antitumoral composition based on immunogenic polypeptide..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antitumoral composition based on immunogenic polypeptide... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1702026