C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/06 (2006.01) A61K 31/7064 (2006.01) A61P 35/00 (2006.01) C07H 19/04 (2006.01) C12Q 1/18 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2307002
Methods of diagnosing and/or of treating tu-mors by administering a nucleoside analogue which is activated by thymidylate synthase and/or thymi-dine kinase enzyme into a diagnostic or toxic metabolite, and uridine analogue compounds, and compositions of same having a pharmaceutically ac-ceptable carrier. For diagnostic applications, com-pounds containing a label and methods of use of such compounds are described.
La présente invention concerne des procédés de diagnostic et/ou de traitement de tumeurs constant à administrer un analogue de nucléoside activé par une enzyme de thymidylate synthase et/ou de thymidine kinase dans un métabolite diagnostique ou toxique, des composés analogues d'uridine, et des compositions de ceux-ci possédant un transporteur pharmaceutiquement acceptable. La présente invention concerne également des composés pour des applications diagnostiques contenant un marqueur et des procédés d'utilisation de ces composés.
Anderson Lawrence
Collins Jerry M.
Katki Aspandiar G.
Klecker Raymond W.
Gowling Lafleur Henderson Llp
The Government Of The United States Of America Represented By The Secre Tary Of The Department Of Health And Hu
LandOfFree
Antitumour uridine analogues does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Antitumour uridine analogues, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antitumour uridine analogues will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1519512