Antiulcer pyrimidine derivatives

Details Antiulcer pyrimidine derivatives Antiulcer pyrimidine derivatives

C - Chemistry, Metallurgy

07

D

167/211, 260/260

C07D 401/12 (2006.01) A61K 31/505 (2006.01) C07D 413/14 (2006.01)

Patent

CA 1317946

72222-107 ABSTRACT OF THE DISCLOSURE 8-(2-Pyrimidylsulfinyl)quinolines of the formula : (I) Image (wherein Q is H, F, C1 NO2, NH2, CF3, alkanoylamino, alkoxy, alkyl or dialkylamino; X is H, alkyl, alkoxy, phenoxy, benzyloxy, cycloalkoxy, amino, mono- or dialkylamino, anilino, N-alkylanllino, benzylamino, N-alkylbenzylamino, morpholino, piperidino or pyrrolidino; Y is H, E, C1 Br, alkoxy or alkyl; Z is H, alkyl or alkoxy; and n is an integer of O to 2) are inhibitor of the H+/K+ ATPase enzyme and are useful in the treatment of ulcers.

590948

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