Antiviral agent for drug-resistant virus

Details Antiviral agent for drug-resistant virus Antiviral agent for drug-resistant virus

C - Chemistry, Metallurgy

07

H

C07H 19/207 (2006.01) A61K 31/675 (2006.01) A61P 31/12 (2006.01) C07D 473/24 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2360824

2-amino-6-arylthiopurinephosphonate used in the antiviral agent of the present invention has no toxicity such as bone marrow cell growth inhibition or mutagenicity, and has a high antiviral activity, oral absorbency and safety. Furthermore, the compound of the present invention is effective for a mutant virus which is known to exhibit resistance to the conventional antiviral agents. Therefore, the present invention can provide a useful antiviral agent which leads to the establishment of a method for treating hepatitis B, which is a medically important object.

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