A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/70 (2006.01) A61K 31/505 (2006.01) A61K 31/52 (2006.01) A61K 31/66 (2006.01) A61P 31/12 (2006.01) A61P 31/18 (2006.01)
Patent
CA 2125054
- 1 - Abstract The present invention is directed to antiviral agents which comprise as active ingredients one or more 2', 3'-dideoxyribonucleosides or phosphoric esters thereof and a 6-benzyl-1-ethoxymethyl-5-substituted uracil derivative of the formula (I): Image (1) wherein X is oxygen or sulfur atom; R1 is ethyl or isopropyl; R2 and R3 are independently hydrogen atom, C1 - C3 alkyl or halogen atom. These compounds can inhibit HIV reverse transcriptase through different mechanisms and are synergistic in combination.
Ubasawa Masaru
Yuasa Satoshi
Kirby Eades Gale Baker
Mitsubishi Chemical Corporation
Mitsubishi Kasei Corporation
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