Antiviral antibiotic bu-3889v

Details Antiviral antibiotic bu-3889v Antiviral antibiotic bu-3889v

C - Chemistry, Metallurgy

12

P

C12P 19/44 (2006.01) A61K 35/74 (2006.01) C07G 11/00 (2006.01) C07H 15/00 (2006.01) C12N 1/20 (2006.01) C12P 1/06 (2006.01) A61K 31/71 (1990.01)

Patent

CA 2020800

A B S T R A C T Production of an antiviral antibiotic complex, BU-3889V and its bioactive components A1, A2, A3, D1, D2 and D3, by fermentation of a BU-3889V producing strain of the new microorganism Amycolatopsis orientalis ATCC-53884 is disclosed. Complex BU-3889V is recovered and the components separated by the use of ion exchange chromatography techniques. The bioactive components are characterized by their physico-chemical characterizing properties. The products have been found to be effective to inhibit viruses including herpes simplex virus, human immunodeficiency virus (HIV) and influenza virus.

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