Antiviral antibiotic bu-4628v and preparation thereof

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 21/00 (2006.01) A61K 38/16 (2006.01) C07K 14/36 (2006.01) C12N 1/20 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2110854

ABSTRACT There is provided a new antiviral antibiotic designated herein as BU-4628V which is produced by fermentation of a BU-4628V-producing strain of a new microorganism, Streptomyces sp. ATCC 55286. Antibiotic BU-4628V is recovered and purified from the fermentation broth by use of extraction and chromatography techniques. BU-4628V has been found to have some antibacterial activity and inhibits the growth of HIV and HSV viruses.

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