Antiviral antitumor antimetastatic immune system enhancing...

Details Antiviral antitumor antimetastatic immune system enhancing... Antiviral antitumor antimetastatic immune system enhancing...

C - Chemistry, Metallurgy

07

H

167/202, 260/229

C07H 19/23 (2006.01) A61K 31/70 (2006.01) C07H 19/24 (2006.01)

Patent

CA 1319931

ANTIVIRAL ANTITUMOR IMMUNE SYSTEM ENHANCING NUCLEOSIDES AND NUCLEOTIDES ABSTRACT OF DISCLOSURE Compounds of the structure: Image wherein R4, R5, R6 and R7 individually are H, OH or C1-C18 O-acyl and R3 is H, C1-C18 acyl or Image ; or R5 and R7 are H or OH, R6 is H and together R3 and R4 are Image ; and X is =O or =S; Y is -OH, -SH, -NH2 or halogen; and Z is H, -NH2, -OH or halogen; wherein halogen is Cl or Br; or a pharmaceutically acceptable salt thereof are useful as antivirals, antitumors, antimetastatics and as immune system enhancers.

576416

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