Antiviral combinations

A - Human Necessities – 61 – K

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A61K 31/495 (2006.01) A61K 31/485 (2006.01) C07D 241/44 (2006.01) C07D 241/52 (2006.01)

Patent

CA 1121268

X-5244-3 -1- Abstract A pharmaceutical composition comprising as active ingredient a combination of antiviral drugs, one of which is a quinoxaline of the formula Image I wherein each X is separately C1 and R is ethyl and the other is a hindered amine of the group consisting of cyclooctylamine, 2-aminobicyclo[2.2.1]heptane, 2-aminonorbornane or a substituted adamantane of the formula Image wherein R1 is NH2 or Image and R2 is H or CH3 and excipients is useful for suppressing influenza virus infections in mammals.

337951

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