Antiviral combinations containing the carbocyclic nucleoside...

A - Human Necessities – 61 – K

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A61K 31/52 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2289654

The present invention relates to therapeutic combinations of (-)-(1S, 4R)-4-[2- amino-6- (cyclopropylamino)-9H-purin-9-yl] -2-cyclopentene-1-methanol (1592U89) and HIV protease inhibitors which have anti-HIV activity. The present invention is also concerned with pharmaceutical compositions containing said combinations and their use in the treatment of HIV infections.

L'invention concerne des combinaisons thérapeutiques de (-)-(1S, 4R)-4-[2-amino-6- (cyclopropylamino)-9H-purin-9-yl] -2-cyclopentène-1-méthanol (1592U89) et des inhibiteurs de la protéase du VIH présentant une activité anti-VIH. L'invention concerne également des compositions pharmaceutiques contenant lesdites combinaisons et leur utilisation dans le traitement des infections par le VIH.

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