Antiviral compositions and method for their use

C - Chemistry – Metallurgy – 07 – F

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C07F 15/06 (2006.01) A61K 31/555 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2123691

Methods of use and antiviral compounds and compositions, of compounds having formula (II), wherein each A may be the same ar different, and is alkyl, phenyl or a substituted derivative of a phenyl; Y may be the same or different, and is hydrogen, unbranched alkyl, a halide or a group (a), wherein R is hydrogen, alkoxide, alkyl, or OH; B may be the same or different, and is hydrogen or alkyl; Z is a soluble, pharmaceutically acceptable negative ion; and X may be the same or different, and is an axial ligand selected from the group consisting of moieties having formula (IIa), wherein R1-R9 may be the same or different, and may be hydrogen or lower alkyl, and (IIb), wherein R5-R9 may be the same or different, and may be selected from the group consisting of electron donating groups and electron withdrawing groups, with the proviso that R1-R9 are sufficiently small so as not to prohibit the attachment of the axial ligand to the Co atom due to steric hindrance.

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