Antiviral compounds

Details Antiviral compounds Antiviral compounds

C - Chemistry, Metallurgy

07

D

C07D 215/22 (2006.01) A61K 31/365 (2006.01) A61K 31/38 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) C07D 311/56 (2006.01) C07D 335/06 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07D 417/04 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2091171

2091171 9204326 PCTABS00011 Compounds useful as antiviral agents against DNA-containing viruses, such as herpes group viruses, are disclosed. The compounds are represented by formula (1.0), and their pharmaceutically acceptable salts and solvates; wherein: (A) X is selected from the group consisting of N-R3, O, S, and C(R3)2; (B) R3 is selected from H and a range of substituents; (C) R1 is an etherifying or esterifying group; (D) R2 is selected from a range of substituents; (E) m is 0 or an integer from 1 to 4; and (F) R4 and R5 are the same and are selected from alkyl and acyl groups; together with the pharmaceutically acceptable salts of the compounds of formula (1.0) that are acidic or basic. Pharmaceutical compositions containing compounds represented by Formula (1.0) are disclosed. Also disclosed are methods of treating a viral infection using compounds represented by formula (1.0).

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