Antiviral compounds

C - Chemistry – Metallurgy – 07 – H

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C07H 19/10 (2006.01) A61K 31/70 (2006.01) C07F 9/547 (2006.01) C07F 9/6558 (2006.01) C07F 9/6561 (2006.01) C07H 19/20 (2006.01)

Patent

CA 2028151

- 20 - ABSTRACT ANTIVIRAL COMPOUNDS Compounds of formula I or a pharmaceutically acceptable salt thereof: I Image in which formula R1 represents an aliphatlc hydrocarbyl group; Ar represents a substituted or unsubstituted aromatic nucleus; X represents -SO2- or -CO- and R2 and R3 which may be identical or different represent moieties of formula (a), (b), (c), (d), (e), (f), (g), (h) or (i): Image Image Image (a) (b) (c) Image Image (d) (e) (f) Image (g) Image (h) Image (i) Image -21- wherein B represents the residue of a nucleoside base of formula (A), (G), (C), (H) or (T): Image Image (A) (G (C) Image H; (H) Image (T) provided that when R2 and R3 both represent an unsubstituted moiety of formula (a) B represents the residue of a nucleoside base which is of formula (A), (G), (C) or (H) are of value for their antiviral activity.

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