Antiviral compounds and antihypertensive compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 215/22 (2006.01) A61K 31/365 (2006.01) A61K 31/38 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) C07D 311/16 (2006.01) C07D 311/68 (2006.01) C07D 401/02 (2006.01) C07D 401/06 (2006.01) C07D 405/02 (2006.01) C07D 405/04 (2006.01) C07D 405/12 (2006.01) C07D 407/02 (2006.01) C07D 407/12 (2006.01) C07D 409/02 (2006.01) C07D 409/12 (2006.01) C07D 417/04 (2006.01) C07F 7/18 (2006.01) C07F 9/60 (2006.01)

Patent

CA 2091172

Compounds useful as antihypertensive agents and useful as antiviral agents against viruses,such as herpes group viruses, are disclosed. The compounds are represented by formula (1.0) and their pharmaceutically acceptable salts and solvates. Pharmaceutical compositions containing compounds represented by formula (1.0) are disclosed. Methods of treat- ing a viral infection using compounds represented by formula (1.0) are disclosed. Also disclosed are methods of treating hyper- tension using compounds of formula (1.0) wherein R is selected from the group consisting of H, halogen and -C(O)OR6; and R1 is selected from the group consisting of -ORI4, -O(CH2)aaC(H)3jZj and -O(CH2)hN(RI5)2.

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