Antiviral compounds and pharmaceutical compositions

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 409/04 (2006.01) A61K 31/33 (2006.01) C07D 207/333 (2006.01) C07D 303/32 (2006.01) C07D 405/04 (2006.01) C07D 407/04 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 473/00 (2006.01) C07D 475/00 (2006.01) C07F 5/02 (2006.01) C07J 71/00 (2006.01)

Patent

CA 2155067

The present invention provides novel compounds and novel pharmaceutical compositions which possess antiviral activity, particularly against retroviruses. The compositions comprise a pharmaceutically acceptable carrier, diluent or excipient, and an effective antiviral amount, preferably anti-retroviral effective amount of a compound having the following generic formula: Image wherein X is selected from the group consisting of O and S; n is an integer of from 1 to 9, each R1 is independently selected from the group consisting of hydrogen, C1 to C4 lower alkyl group (or others); and Ring is a C2 to C6 ring system containing up to three double bonds, and up to three heteroatoms selected from nitrogen, sulfur and/or oxygen.

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