Antiviral drugs for treatment of arenavirus infection

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/04 (2006.01) A61K 31/4192 (2006.01) A61K 31/437 (2006.01) A61P 31/14 (2006.01) C07D 249/18 (2006.01)

Patent

CA 2698075

Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family such as Lassa fever, Argentine hemorrhagic fever, Bolivian hemorrhagic fever, and Venezuelan hemorrhagic fever.

L'invention concerne des composés, des procédés et des compositions pharmaceutiques destinés à traiter des infections virales, par l'administration de certains composés en quantités thérapeutiquement efficaces. L'invention concerne aussi des procédés de préparation de ces composés et des procédés d'utilisation de ces composés et de ces compositions pharmaceutiques. L'invention concerne en particulier le traitement et la prophylaxie d'infections virales telles que celles causées par la famille arénavirus telles que la fièvre de Lassa, la fièvre hémorragique argentine, la fièvre hémorragique bolivienne, et la fièvre hémorragique vénézuélienne.

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