A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4184 (2006.01) A61P 31/12 (2006.01)
Patent
CA 2651943
Compounds, methods and pharmaceutical compositions for treating viral : infections, by administering certain novel compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and method's using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, Pichinde, and LCMV), Filoviridae (Ebola and Marburg viruses), Flaviviridae (yellow fever, Omsk hemorrhagic fever and Kyasanur Forest disease viruses), andBunyaviridae (Rift Valley fever).
L'invention concerne des composés, des procédés et des compositions pharmaceutiques destinés à traiter des infections virales en administrant certains nouveaux composés en des quantités thérapeutiquement efficaces. Elle concerne également des procédés de préparation des composés ainsi que des procédés d'utilisation des composés et des compositions pharmaceutiques les contenant. En particulier, l'invention concerne le traitement et la prévention d'infections virales telles que celles provoquées par des virus de fièvre hémorragique, c'est-à-dire des virus comprenant non limitativement des arénaviridés (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, Pichinde et LCMV), des filoviridés (virus Ebola et Marburg), des flaviviridés (virus de la fièvre jaune, de la fièvre hémorragique d'Omsk et de la maladie de la forêt de Kyasanur) et des bunyaviridés (fièvre de la vallée du Rift).
Amberg Sean
Bolken Tove
Dai Dongcheng
Hruby Dennis E.
Amberg Sean
Bolken Tove
Dai Dongcheng
Dimock Stratton Llp
Hruby Dennis E.
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