Antiviral drugs for treatment or prevention of dengue infection

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/517 (2006.01) A61K 31/395 (2006.01) A61P 31/12 (2006.01) A61P 31/14 (2006.01) A61K 31/675 (2006.01) A61K 31/7056 (2006.01) A61K 38/21 (2006.01) A61K 39/12 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2688194

Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by flavivirus is disclosed, i.e., including but not limited to, Dengue virus, West Nile virus, yellow fever virus, Japanese encephalitis virus, and tick-borne encephalitis virus.

L'invention concerne des composés, procédés et compositions pharmaceutiques pour traiter des infections virales, par administration de certains composés dans des quantités thérapeutiquement efficaces. Des procédés de préparation des composés et des procédés d'utilisation des composés et des compositions pharmaceutiques de ceux-ci sont également révélés. En particulier, le traitement et la prophylaxie d'infections virales telles qu'induites par la flavivirose sont révélés, c'est-à-dire comprenant sans s'y limiter, le virus de la dengue, le virus du Nil occidental, le virus de la fièvre jaune, le virus de l'encéphalite japonaise et le virus de l'encéphalite de la taïga.

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