Antiviral guanosine-rich oligonucleotides

Details Antiviral guanosine-rich oligonucleotides Antiviral guanosine-rich oligonucleotides

C - Chemistry, Metallurgy

07

H

C07H 21/02 (2006.01) A61K 31/70 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2161243

A method and composition for treating viral infection in vitro and in vivo using guanosine-rich oligonucleotides. The oligonucleotides have sufficient guanosine to form a guanosine tetrad. They can be composed of at least about 40 % guanosine nucleotides. Also provided are oligonucleotides of at least two runs of at least two guanosines. Also provided are guanosine-rich oligonucleotides and methods for treating viral infections in humans and a method for designing guanosine-rich oligonucleotides having anti-viral activity.

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