Antiviral, highly water soluble, stable, crystalline salts...

Details Antiviral, highly water soluble, stable, crystalline salts... Antiviral, highly water soluble, stable, crystalline salts...

C - Chemistry, Metallurgy

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C07H 19/04 (2006.01) A61K 31/505 (2006.01) A61K 31/52 (2006.01) A61K 31/70 (2006.01) A61P 31/12 (2006.01) C07D 405/04 (2006.01) C07D 473/30 (2006.01) C07H 19/06 (2006.01) C07H 19/073 (2006.01) C07H 19/16 (2006.01) C07H 19/173 (2006.01)

Patent

CA 2016765

Very highly water soluble, stable, crystalline salts of 2',3'-dideoxy-2',3'-didehydrothymidine of the formula (see fig. I) 2',3'-dideoxyinosine of the formula (see fig.II) and 2',3'-dideoxy-2'-fluoroinosine of the formula (see fig.III) wherein X is an organic or inorganic cation are prepared. Such salts are useful as antiviral agents.

Préparation de sels cristallisés stables, très hydrosolubles, de 2',3'-didésoxy-2',3'-didéshydrothymidine de formule (voir fig. I), de 2',3'-didésoxyinosine de formule (voir fig. II), et de 2',3'-didésoxy-2'-fluoro-inosine de formule (voir fig.III), où X est un cation organique ou minéral. Ces sels sont utiles comme agents antiviraux.

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