Antiviral macrocyclic compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 257/02 (2006.01) A61K 31/395 (2006.01) A61P 31/12 (2006.01) C07D 255/00 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/10 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 471/06 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2336634

The present invention is drawn to novel antiviral compounds, pharmaceutical compositions and their use. More specifically this invention is drawn to derivatives of monocyclic polyamines which have activity in standard tests against HIV- or FIV-infected cells as well as other biological activity related to binding of ligands to chemokine receptors that mediate a number of mammalian embryonic developmental processes.

La présente invention concerne de nouveaux composés antiviraux, des compositions pharmaceutiques et leur utilisation. Plus spécifiquement, cette invention concerne des dérivés de polyamines monocycliques présentant une activité dans les tests normalisés sur des cellules inffectées par VIH ou VIF ainsi qu'une autre activité biologique rapportée à la liaison de ligands à des récepteurs de chémokine induisant un certain nombre de processus de développement embryonnaire mammifère.

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