Antiviral monocyclic polyamines

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/12 (2006.01) A61K 31/395 (2006.01) C07D 255/02 (2006.01) C07D 257/02 (2006.01) C07D 259/00 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 471/08 (2006.01) C07D 487/08 (2006.01) C07D 513/08 (2006.01)

Patent

CA 2178272

Macrocyclic compounds having a total of 9 to 24 ring members and from 3 to 6 optionally substituted amine nitrogens spaced by two or more optionally substituted carbon atoms from each other, which may optionally comprise a fused aromatic or heteroaromatic ring, linked to a substituted methylamine chain, show good selectivity against HIV-1 and HIV-2 in in vitro tests.

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