C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 311/92 (2006.01) A61K 31/12 (2006.01) A61K 31/335 (2006.01) A61K 31/35 (2006.01) A61K 31/352 (2006.01) A61K 31/37 (2006.01) A61K 38/17 (2006.01) A61K 38/21 (2006.01) A61K 45/06 (2006.01) C07C 46/00 (2006.01) C07C 46/10 (2006.01) C07C 50/32 (2006.01) C07D 311/56 (2006.01)
Patent
CA 2155020
The present invention provides novel antiviral naphthoquinone compounds, which may be isolated from plants of the genus Conospermum or synthesized chemically, in accordance with the present inventive methods. The antiviral naphthoquinone compounds, derivatives thereof, and prodrugs thereof, may be used alone or in combination with other antiviral agents in compositions, such as pharmaceutical compositions, to inhibit the growth or replication of a virus, such as a retrovirus, in particular a human immunodeficiency virus, specifically HIV-1 or HIV-2, in the treatment or prevention of viral infection.
Boyd Michael R.
Cardellina John H. II
Cragg Gordon M.
Decosterd Laurent A.
Gustafson Kirk R.
Department O. F. Health And Human Services The United States Of America Represented By The Secretary
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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