Antiviral nucleoside compounds

Details Antiviral nucleoside compounds Antiviral nucleoside compounds

C - Chemistry, Metallurgy

07

H

C07H 19/213 (2006.01) A61K 31/7064 (2006.01) A61K 31/7076 (2006.01) A61P 31/14 (2006.01) C07H 19/11 (2006.01)

Patent

CA 2706432

Compounds having the formula I or II wherein R1, R2, B, and V are as defined herein are Hepatitis C virus NS5b poly-merase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.

L'invention concerne des composés répondant à la formule I ou II, dans lesquelles R1, R2, B, et V sont tels que définis ici, et qui sont des inhibiteurs de polymérase NS5b du virus de l'hépatite C. Elle concerne également des compositions et des procédés de traitement d'une infection par le HCV et d'inhibition de la réplication de HCV.

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