Antiviral polynucleotide conjugates

Details Antiviral polynucleotide conjugates Antiviral polynucleotide conjugates

C - Chemistry, Metallurgy

12

Q

C12Q 1/70 (2006.01) A61K 31/70 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2116465

ABSTRACT Ligand-binding duplexed structures having significantly enhanced stability underphysiological conditions are described. The structures are provided in the form of polynucleotide conjugates capable of adopting a duplexed structure, in which annealable polynucleotide strands are coupled covalently at one or both ends through a chemical linker which establishes a stabilizing bridge between strands. The present polynucleotide conjugates have therapeutic utility against viral infection as the polynucleotide strands thereof define a binding site for a viral regulatory protein, thereby inactivating the protein and preventing viral replication from occurring.

Affiliated with

Also associated with

Rating

Antiviral polynucleotide conjugates does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antiviral polynucleotide conjugates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antiviral polynucleotide conjugates will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1402815