Antiviral therapy on the basis of rna interference

Details Antiviral therapy on the basis of rna interference Antiviral therapy on the basis of rna interference

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2482395

The invention concerns a new gene therapy for treatment of animals and humans which suffer from an infection with a chronic virus such as HIV or HCV. It can also be used prophylacticly to prevent chronic infection. The therapy makes use of a nucleotide construct stably integrated in the genome of the target cells of the virus, which is able to produce a single transcript or multiple transcripts capable of forming a double-stranded RNA which inhibits replication of the virus in situ.

Cette invention concerne une nouvelle thérapie génique destinée au traitement d'animaux ou d'humains atteints d'une infection par un virus, tel que le HIV ou le VHC. Elle peut également être utilisée à des fins prophylactiques pour prévenir une infection chronique. La thérapie de l'invention met en oeuvre une construction nucléotidique intégrée de façon stable dans le génome des cellules cibles du virus pour produire un transcrit simple ou un transcrit multiple pouvant former un ARN bicaténaire qui inhibe la réplication du virus in situ.

Affiliated with

Also associated with

Rating

Antiviral therapy on the basis of rna interference does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antiviral therapy on the basis of rna interference, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antiviral therapy on the basis of rna interference will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1620770