Antiviral topical formulations in the form of a bio-adhesive...

A - Human Necessities – 61 – K

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Details

A61K 9/06 (2006.01) A61K 31/522 (2006.01) A61K 47/32 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2698498

The invention relates to topical formulations in the form of a bioadhesive hydrophilic gel comprising acyclovir as active ingredient, Sodium hyaluronate and an acrylic polymer. Said formulations improve the local administration of acyclovir in the treatment of herpes infections, because they possess good properties of adherence to the mucosa and high resistance to physiological removal mechanisms.

La présente invention concerne des formulations topiques sous forme de gel hydrophile bioadhésif comprenant de l'acyclovir comme principe actif, du hyaluronate de sodium et un polymère acrylique. Lesdites formulations améliorent l'administration locale d'acyclovir dans le traitement d'infections à herpes, car elles possèdent de bonnes propriétés d'adhérence à la muqueuse et une forte résistance aux mécanismes d'élimination physiologiques.

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