Antiviral tricyclic benzocyclopyrimidine derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 239/70 (2006.01) A61K 31/505 (2006.01) C07D 491/048 (2006.01)

Patent

CA 1321196

Abstract of the Disclosure Compounds having antiviral activity and having the formula: Image Image wherein each X is (CH2)n where 1 ? n ? 3; where R4 is lower alkyl; CH2S: or CH2O; and R3 and R5, independently, are H, fluoro, nitro, amino, alkylamino, dialkylamino, arylamino, acylamido, carboxy, azido, lower alkoxy, trimethylsulfonyl, trifluoro- methansesulfonyl, or lower alkoxycarbonyl, provided that when X is (CH2)2, R3 cannot be H; or a pharmaceutically acceptable salt thereof.

570047

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