Apaf-1, the ced-4 human homolog, an activator of caspase-3

Details Apaf-1, the ced-4 human homolog, an activator of caspase-3 Apaf-1, the ced-4 human homolog, an activator of caspase-3

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2293724

Novel polypeptides, designated Apaf-1, which are capable of modulating apoptosis are provided. Compositions including Apaf-1 chimeras, nucleic acid encoding Apaf-1, and antibodies to Apaf-1 are also provided.

La présente invention concerne de nouveaux polypeptides appelés Apaf-1, capables de moduler une apoptose. La présente invention concerne également des compositions comprenant des chimères d'Apaf-1, un acide nucléique codant Apaf-1 et des anticorps contre d'Apaf-1.

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