A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/19 (2006.01) C12N 5/071 (2010.01) A61K 9/19 (2006.01) A61K 38/16 (2006.01) A61K 45/06 (2006.01) A61K 47/18 (2006.01) C07K 14/52 (2006.01) C12P 21/02 (2006.01) A61K 31/198 (2006.01)
Patent
CA 2466054
The inventions include Apo2L/TRAIL formulations and methods of using such formulations. Lyophilized and crystal formulations of Apo-2L/TRAIL which are stable and have improved Apo2L/TRAIL trimer formation are provided. Methods of making Apo-2L/TRAIL formulations, as well as devices and kits containing such formulations are also provided.
L'invention concerne des formulations Apo2L/TRAIL et des procédés visant à utiliser ces formulations. Elle concerne des formulations lyophilisées et cristallines de Apo-2L/TRAIL stables et possédant une formation trimère Apo2L/TRAIL améliorée. Elle concerne également des procédés servant à préparer ces formulations, ainsi que des dispositifs et des trousses contenant ces formulations.
Flores Heather
Lin Tanya P.
Matthews Timothy C.
Pai Roger
Shahrokh Zahra
Genentech Inc.
Smart & Biggar
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