Apo-2 ligand/trail variants and uses thereof

Details Apo-2 ligand/trail variants and uses thereof Apo-2 ligand/trail variants and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2489348

The disclosure provides Apo-2 ligand variant polypeptides. Methods of making and chemically modifying Apo-2 ligand variant polypeptides are also provided. In addition, formulations of Apo-2 ligand variant polypeptides are provided. In addition, therapeutic methods for using Apo-2 ligand variant polypeptides are provided.

Cette invention se rapporte ~ des polypeptides variants du ligand Apo-2, ~ des proc~d~s pour produire et modifier chimiquement ces polypeptides variants du ligand Apo-2, ~ des formulations de ces polypeptides variants du ligand Apo-2, ainsi qu'~ des proc~d~s th~rapeutiques utilisant ces polypeptides variants du ligand Apo-2.

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