Apo-3 ligand

Details Apo-3 ligand Apo-3 ligand

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/19 (2006.01) C07K 14/705 (2006.01) C07K 16/24 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2305713

A tumor necrosis factor and lymphotoxin homolog having apoptotic activity, identified as Apo-3 Ligand, is provided. Nucleic acid molecules encoding Apo-3 ligand, chimeric molecules and antibodies to Apo-3 Ligand are also provided.

L'invention concerne un facteur de nécrose des tumeurs et un homologue de lymphotoxine possédant une activité apoptotique, identifiés comme étant le ligand Apo-3. L'invention concerne également des molécules d'acide nucléique codant le ligand Apo-3, des molécules chimériques et des anticorps au ligand Apo-3.

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