Apo ai polypeptides, antibodies, and immunoassays

Details Apo ai polypeptides, antibodies, and immunoassays Apo ai polypeptides, antibodies, and immunoassays

C - Chemistry, Metallurgy

07

K

C07K 14/775 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) C07K 4/12 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 16/18 (2006.01) G01N 33/566 (2006.01) G01N 33/577 (2006.01) G01N 33/92 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2084677

The present invention describes an Apo AI polypeptide capable of immunologically mimicking an Apo AI epitope. The polypeptide is useful in diagnostic methods and systems for detecting Apo AI in vascular fluid samples, and for preparation of anti-Apo AI antibodies. In addition, the polypeptide is useful in therapeutic methods for increasing esterified cholesterol in a hu- man patient.

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