Apoe4 domain interaction inhibitors and methods of use thereof

Details Apoe4 domain interaction inhibitors and methods of use thereof Apoe4 domain interaction inhibitors and methods of use thereof

A - Human Necessities

61

L

A61L 9/04 (2006.01) A61K 31/655 (2006.01)

Patent

CA 2622952

The present invention provides compounds that inhibit apoE4 domain interaction; and compositions, including pharmaceutical compositions, comprising the compounds. The present invention provides methods of treating apoE4-related disorders. The methods generally involve administering to an individual in need thereof a therapeutically effective amount of an apoE4 domain interaction inhibitor.

La présente invention concerne des composés qui inhibent de l'interaction du domaine apoE4 ainsi que des compositions, notamment pharmaceutiques, qui renferment ces composés. L'invention concerne également des méthodes de traitement de troubles en rapporta avec apoE4. Ces méthodes consistent généralement à administrer à un individu qui en a besoin une dose efficace au plan thérapeutique d'un inhibiteur de l'interaction du domaine apoE4.

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