Apomorphine derivatives and methods for their use

Details Apomorphine derivatives and methods for their use Apomorphine derivatives and methods for their use

C - Chemistry, Metallurgy

07

D

C07D 221/18 (2006.01) A61K 31/473 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2405419

Apomorphine derivative compounds; pharmaceutically active compositions of apomorphine derivative compounds; and the use of apomorphine derivative compounds in methods for treating sexual dysfunction or for enhancing apormorphine effectivenesss for patients treated with apomorphine are disclosed. The apomorphine derivatives may be esters, ethers, amides, mixed anhydrides, hemiacetals, glucuronates, sulfates or phosphonates. A preferred apomorphine derivative is norapomorphine.

L'invention porte sur des composés de dérivés d'apomorphine, sur leurs compositions actives d'un point de vue pharmaceutique et sur leur utilisation dans des procédés visant à traiter la dysfonction sexuelle ou à améliorer l'efficacité de l'apomorphine chez des patients traités avec l'apomorphine. Les dérivés d'apomorphine peuvent être des esters, éthers, amides, anhydrides mixes, hémi-acétals, glucuronates, sulfates ou phosphonates. Un dérivé d'apomorphine est la norapomorphine.

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