Apoptosis inducers

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/24 (2006.01) A61K 31/715 (2006.01) A61K 31/737 (2006.01) C08B 37/00 (2006.01) C12P 19/04 (2006.01) C12P 19/14 (2006.01)

Patent

CA 2243543

Apoptosis inducers, anticancer drugs and carcinostatic drugs containing sulfated-fucose-containing polysaccharide(s) and/or degradation product(s) thereof, and a method for inducing apoptosis by using sulfated-fucose- containing polysaccharide(s) and/or degradation product(s) thereof as the active ingredient. A degrading enzyme which is useful in the production of the degradation products of sulfated-fucose-containing polysaccharides.

Cette invention se rapporte à des inducteurs d'apoptose, à des médicaments anticancéreux et à des médicaments cancérostatiques contenant comme principe actif un des polysaccharides à teneur en fucose sulfatée et/ou un ou des produits de dégradation de ceci, ainsi qu'à un procédé permettant d'induire l'apoptose grâce à l'utilisation d'un ou de plusieurs polysaccharides à teneur en fucose sulfatée et/ou d'un de plusieurs produits de dégradation de ceci. Cette invention se rapporte également à une enzyme à action dégradante, qui est utile dans l'obtention des produits de dégradation de ces polysaccharides à teneur en fucose sulfatée.

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