Apoptosis-mimicking synthetic entities and use thereof in...

Details Apoptosis-mimicking synthetic entities and use thereof in... Apoptosis-mimicking synthetic entities and use thereof in...

A - Human Necessities

61

K

A61K 31/685 (2006.01) A61K 9/127 (2006.01) A61K 9/16 (2006.01) A61K 47/48 (2006.01) A61P 19/00 (2006.01) A61P 21/00 (2006.01)

Patent

CA 2319928

Synthetic and semisynthetic bodies having a three-dimensional structure, sized and shaped to resemble apoptotic cells and apoptotic bodies, and having phosphatidyl serine (PS) molecules on the surface thereof, are administered to a patient, to alleviate a variety of disorders such as T-cell mediated disorders (autoimmune conditions). The bodies are believed to trigger an apoptosis-like mechanism in the patient, with consequent down-regulation of Th- 1 response in the patient's immune system.

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