Apoptosis-specific eif-5a and polynucleotides encoding same

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) A61K 31/713 (2006.01)

Patent

CA 2588129

The present invention relates to apoptosis specific eucaryotic initiation factor 5A (eIF-5A), referred to as apoptosis-specific eIF-5A or eIF5-A1, nucleic acids and polypeptides and methods for increasing or decreasing expression of apoptosis-specific eIF-5A. The invention also relates to methods of increasing or decreasing apoptosis.

La présente invention a trait à un facteur d'initiation eucaryote 5A (elF-5A), désigné elF-5A ou elF-5A1 spécifique de l'apoptose, à des acides nucléiques et des polypeptides ainsi qu'à des procédés pour l'accroissement ou la réduction de l'expression d'elF-5A spécifique de l'apoptose. L'invention a également trait à des procédés d'accroissement ou de réduction de l'apoptose.

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