Apparatus and method for concurrent chemical synthesis

G - Physics – 01 – N

Patent

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Details

G01N 35/02 (2006.01) B01J 19/00 (2006.01) B01L 3/00 (2006.01) G01N 35/10 (2006.01)

Patent

CA 2356852

This invention provides an apparatus for preparing chemical libraries. The apparatus includes: (1) a carousel comprising a plurality of reaction mounts having at least one reaction well; (2) a rotator that rotates the carousel step-wise; (3) a fluid delivery system; (4) a drain system; and (5) a programmable computer that controls the operation of the apparatus, including the rotator, the fluid delivery system, the drain system and other systems in the apparatus. The preparation of chemical libraries involves rotating the carousel through a plurality of stations. At each station, a physical step in a reaction protocol is carried out on the reaction wells of the mount docked at the station.

L'invention concerne un appareil servant à préparer des banques chimiques. L'appareil comporte: (1) un carrousel comportant plusieurs supports de réaction présentant au moins un puits de réaction; (2) un rotateur qui fait tourner le carrousel pas-à-pas; (3) un système d'apport de fluide; (4) un système d'évacuation; et (5) un ordinateur programmable commandant le fonctionnement de l'appareil, y compris du rotateur, du système d'apport de fluide, du système d'évacuation et d'autres systèmes de l'appareil. La préparation de banques chimiques comporte une rotation du carrousel par plusieurs stations. A chaque station, une étape physique d'un protocole de réaction est mis en oeuvre dans les puits de réaction du support arrêté à la station.

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