Apparatus and method for continuous real-time trace...

A - Human Necessities – 61 – B

Patent

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A61B 5/04 (2006.01) A61N 1/30 (2006.01)

Patent

CA 2591237

A system and method for transdermal sampling wherein at least one pair of sample electrodes is adapted to provide voltage pulses capable of creating capillary openings in a subject~s stratum corneum. Methods for using a transdermal sampling system by creating capillary openings in a subject~s stratum corneum via the application of a series of voltage pulses to the stratum corneum and contacting at least a portion of at least one of the sample electrodes with interstitial fluid from the capillary openings are also presented.

L'invention concerne un système et un procédé d'échantillonnage transdermique selon lesquels au moins une paire d'électrodes d'échantillonnage est conçue pour fournir des impulsions de tension permettant de créer des ouvertures capillaires dans la couche cornée de l'épiderme d'un sujet. L'invention concerne également des procédés d'utilisation d'un système d'échantillonnage transdermique consistant à créer des ouvertures capillaires dans la couche cornée de l'épiderme par application d'une série d'impulsions de tension sur la couche cornée de l'épiderme et à mettre en contact au moins une partie d'au moins une des électrodes d'échantillonnage avec le liquide interstitiel provenant des ouvertures capillaires.

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