Apparatus and method for delivery of therapeutic and other...

A - Human Necessities – 61 – M

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A61M 5/00 (2006.01) A61F 11/00 (2006.01) A61M 31/00 (2006.01) A61M 39/04 (2006.01) A61M 39/10 (2006.01) A61N 1/372 (2006.01) A61M 25/14 (2006.01)

Patent

CA 2649098

Implantable drug delivery systems target delivery of small volumes of drugs to specific tissues. In some cases, a drug delivery system includes an implantable osmotic pump connected to a drug-containing housing, with that housing connected to a needle, cochlear implant or other type of component for ultimate delivery to the target tissue. In some implementations, a subcutaneous port receives a fluid from an external pump. The port is connected to a needle or other component for delivery of one or more drugs to the target tissue. Both solid and liquid drug formulations can be used. In embodiments using solid drugs, a separate drug vehicle (such as saline) can be used to dissolve a portion of the solid drug, with the drug-loaded vehicle then delivered to the target tissue.

L'invention concerne des dispositifs d'administration de médicaments implantables qui permettent l'administration de petits volumes de médicaments à des tissus spécifiques. Dans certains cas, un dispositif d'administration de médicament inclut une pompe osmotique implantable connectée à un boîtier contenant un médicament, ce boîtier étant connecté à une aiguille, à un implant cochléaire ou à un autre type de composant pour l'administration au tissu cible. Dans certaines implémentations, un orifice sous-cutané reçoit un liquide d'une pompe externe. Ledit orifice est connecté à une aiguille ou autre composant pour l'administration d'un ou de plusieurs médicaments au tissu cible. Des formules de médicaments solides et liquides peuvent être utilisées. Dans des représentations qui utilisent des médicaments solides, un véhicule de médicament séparé (tel que du sérum physiologique) peut être utilisé pour dissoudre une partie du médicament solide, le véhicule chargé de médicament étant ensuite administré au tissu cible.

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