A - Human Necessities – 61 – F
Patent
A - Human Necessities
61
F
A61F 13/00 (2006.01)
Patent
CA 2543084
An apparatus for transdermally delivering a biologically active agent comprising (i) a gel pack containing a hydrogel formulation and (ii) a microprojection member having top and bottom surfaces, a plurality of openings that extend through the microprojection member and a plurality of stratum corneum-piercing microprotrusions that project from said bottom surface of the microprojection member, the microprojection member being adapted to receive the gel pack whereby the hydrogel formulation flows through the microprojection member openings. Preferably, the hydrogel formulation comprises a water-based hydrogel.
L'invention concerne un dispositif qui permet d'administrer un agent biologiquement actif par voie transdermique qui comprend: (a) un dispositif de gel qui contient une formulation d'hydrogel et (b) un élément de microprojection traversé par une pluralité de trous et pourvu de surfaces supérieure et inférieure ainsi que d'une pluralité de protubérances microscopiques qui percent la couche cornée de l'épiderme et qui dépassent de la surface inférieure de l'élément de microprojection; l'élément de microprojection étant adapté pour recevoir le dispositif de gel. La formulation d'hydrogel s'écoule par les trous de l'élément de microprojection. De préférence, la formulation d'hydrogel contient une base aqueuse.
Cormier Michel J.n.
Johnson Juanita
Lin Weiqi
Nyam Kofi
Alza Corporation
Borden Ladner Gervais Llp
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