Apparatus and method for inhibiting restenosis by applying...

A - Human Necessities – 61 – B

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A61B 17/22 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2320300

A system and method for inhibiting restenosis by compromising the migration, viability and adhesion of mammalian smooth muscle cells (SMC). The system includes an ultrasonic energy source; a transmitter for transmitting the ultrasonic energy to the SMC and a drug delivery spectrum for delivering drugs to the smooth mucles cells. This system and method is especially useful in the prevention of restenosis in a blood vessel of a mammal associated with the migration of SMC in the blood vessel following vascular intervention, such as angioplasty.

L'invention concerne un système et un procédé permettant d'inhiber une resténose en empêchant la migration, la viabilité et l'adhérence de cellules musculaires lisses (SMC) de mammaliens. Le système comprend une source d'énergie ultrasonore; un émetteur destiné à émettre l'énergie ultrasonore vers les SMC et un spectre d'administration de médicaments permettant d'introduire les médicaments dans les cellules musculaires lisses. Ces système et procédé sont notamment utiles pour la prévention d'une resténose dans le vaisseau sanguin d'un mammalien associée à la migration de SMC dans le vaisseau sanguin suite à une intervention vasculaire, telle qu'une angioplastie.

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