Apparatus and method for multiple synthesis of organic...

Details Apparatus and method for multiple synthesis of organic... Apparatus and method for multiple synthesis of organic...

B - Operations, Transporting

01

J

B01J 19/00 (2006.01) B25J 9/16 (2006.01) C07K 1/04 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2211029

A solid phase synthesis system is provided by employing a fully automated robot (20) that operates with a novel timing protocol executed by a computer (25) for handling multiple synthetic tasks efficiently. The fully automated robot (20) moves along a track (35) and is equipped with a gripper arm (30) which can pick up, position, and operate syringes (40, 60) which can contain solid supports and amino acid reactants. The novel timing protocol is realized by performing steps in the synthesis cycles for different compounds, such as peptides, concurrently rather than on a sequential basis.

Système de synthèse en phase solide utilisant un robot (20) entièrement automatisé qui fonctionne avec un nouveau protocole de synchronisation exécuté par un ordinateur (25) pour traiter efficacement de multiples tâches de synthèse. Le robot (20) entièrement automatisé se déplace le long d'un rail (35) et comporte un bras de préhension (30) qui peut saisir, placer et faire fonctionner des seringues (40, 60) pouvant contenir des supports solides et des réactifs d'acide aminé. Le nouveau protocole de synchronisation est effectué en exécutant des étapes simultanément plutôt que séquentiellement au cours des cycles de synthèse pour différents composés, tels que les peptides.

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