Apparatus and method for piercing skin with microprotrusions

Details Apparatus and method for piercing skin with microprotrusions Apparatus and method for piercing skin with microprotrusions

A - Human Necessities

61

M

A61M 37/00 (2006.01)

Patent

CA 2602548

A method and device are described for applying a microprotrusion member (44) including a plurality of microprotrusions (90) to the stratum corneum with impact. The method and device are used to improve transport of an agent across the skin for agent delivery or sampling. The applicator (10, 60, 80) causes the microprotrusion member (44) to impact the stratum corneum with a certain amount of impact determined to effectively pierce the skin with the microprotrusions (90). The preferred applicator (10, 60, 80) impacts the stratum corneum with the microprotrusion member (44) with an impact of at least 0.05 joules per cm2 of the microprotrusion member (44) in 10 msec or less.

L'invention concerne un procédé et un appareil qui permettent d'appliquer par impact un élément (44) à microprotubérances comprenant une pluralité de microprotubérances (90) sur la couche cornée. Ce procédé et ce dispositif servent à améliorer le transport d'un agent à travers la peau de manière à permettre l'administration ou le prélèvement d'agents. L'applicateur (10, 60, 80) amène l'élément (44) à microprotubérances au contact de la couche cornée avec un impact calculé de manière à produire une perforation efficace la peau par les microprotubérances (90). L'applicateur (10, 60, 80) préféré de l'invention applique l'élément (44) à mircroprotubérances sur la couche cornée avec un impact d'au moins 0,05 joules par cm2 de l'élément (44), pendant une durée égale ou inférieure à 10 msec.

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